This was a 2005 roast of Rahm Emanuel at a benefit for CURE which is a Chicago-based non-profit that raises money for research in pediatric epilepsy. Susan Axelrod, the founder, is married to David Axelrod, Obama's campaign strategist.
I couldn't figure out how to post this video despite numerous tries, but check it out:
Wow. It's really so cool to see our next PRESIDENT standing in front of the word EPILEPSY. Maybe we'll get somewhere.